Efficacy of Chlorophyllin on Tobacco Induced Chromosomal Aberrations in Rats
نویسنده
چکیده
The present study has investigated the cytoprotective effects of chlorophyllin in tobacco induced chromosomal aberrations in bone marrow of rats. Chromosomal aberrations per cell and percent aberrant cells were observed to calculate genotoxic action of tobacco. Oral treatment with different doses of chln was able to reduce chromosomal aberrations significantly at the pre-treatment level and concurrent treatment level in tobacco treated animals. The present study thus demonstrates the cytoprotective role of Chlorophyllin in tobacco induced chromosomal aberrations in rats (Rattus rattus).
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